Liver and intrahepatic bile ducts - tumor
Other malignancies

Topic Completed: 1 February 2012

Revised: 28 January 2019, last major update February 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Leiomyosarcoma[TI] liver[TI]

Deepali Jain, M.D.
Page views in 2019: 331
Page views in 2020 to date: 53
Cite this page: Jain D. Leiomyosarcoma. website. Accessed April 1st, 2020.
Definition / general
  • Rare (< 30 cases reported) aggressive malignant smooth muscle neoplasm, usually postmenopausal women, characterized by neoplastic spindle cells (IARC: 8890 / 3 Leiomyosarcoma, NOS [Accessed 4 December 2017])
  • Tumors either primary in liver or arise in ligamentum teres or inferior vena cava
  • Associated with HIV, posttransplantation in children and Budd-Chiari syndrome
  • Usually causes death within 2 years
Case reports
Clinical images

Images hosted on other servers:

67 year old man

Microscopic (histologic) images

Images hosted on other servers:

Liver metastases of
rectal carcinoma (left)
and primary hepatic
leiomyosarcoma (right)

67 year old man with 1.3 kg mass

Differential diagnosis
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