Liver & intrahepatic bile ducts tumor
Other malignancies
Well differentiated neuroendocrine tumor


Topic Completed: 1 February 2012

Minor changes: 6 December 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Carcinoid tumor[TI] liver[TI]

Deepali Jain, M.D.
Page views in 2019: 957
Page views in 2020 to date: 656
Cite this page: Jain D. Well differentiated neuroendocrine tumor. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livertumorcarcinoid.html. Accessed July 13th, 2020.
Definition / general
  • Very rare as primary hepatic tumor (< 100 cases reported); usually represents metastasis from GI tumor (small intestinal primaries may be very small)
  • Slightly more frequent in females
  • Rarely associated with Zollinger-Ellison syndrome, VIP production
  • Indolent low grade clinical course with prolonged survival but recurs or metastasizes more frequently than appendiceal carcinoids (Arch Pathol Lab Med 2003;127:1200)
Terminology
  • Previously termed carcinoid tumor
Case reports
Treatment
  • Surgical resection
Gross images

Images hosted on other servers:

62 year old woman
with tan gray tumor
that has soft, fish
flesh cut surface

Microscopic (histologic) description
  • Nested, trabecular or microacinar architecture
  • Composed of small, uniform tumor cells with granular chromatin and round nuclei
  • Often stromal hyalinization
Microscopic (histologic) images

Images hosted on other servers:

62 year old woman with primary hepatic carcinoid tumor

Primary liver tumor in patient with Zollinger-Ellison syndrome

Liver metastases from colon primary

A / B: liver metastases from lung primary

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