Liver and intrahepatic bile ducts - tumor
Other malignancies
Carcinosarcoma



Topic Completed: 1 February 2012

Revised: 28 January 2019, last major update February 2012

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PubMed Search: Carcinosarcoma[TI] liver[TI]


Deepali Jain, M.D.
Page views in 2018: 251
Page views in 2019 to date: 244
Cite this page: Jain D. Carcinosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livertumorcarcinosarcoma.html. Accessed November 18th, 2019.
Definition / general
  • Malignant tumor containing intimate mixture of carcinomatous (either hepatocellular carcinoma or cholangiocellular carcinoma) and sarcomatous elements; sarcomatous component may be chondrosarcomatous, fibrosarcoma, leiomyosarcomatous, osteosarcoma, rhabdomyosarcoma, undifferentiated (IARC: 8980 / 3 Carcinosarcoma, NOS [Accessed 30 November 2017])
  • Also called "malignant mixed tumor"
  • Predominantly older men
  • Risk factors similar to HCC, including cirrhosis, hepatitis B infection
  • Very poor prognosis due to sarcomatous component (Am J Surg Pathol 2007;31:817)
Case reports
Gross images

Images hosted on other servers:

Gray white tumor with necrosis

Microscopic (histologic) images

Images hosted on other servers:

Tubular structures and chondrosarcoma

Various images

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