Liver and intrahepatic bile ducts - tumor
Benign tumors / conditions
Castleman disease




Topic Completed: 1 February 2012

Revised: 24 January 2019, last major update February 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Castleman disease liver

Page views in 2018: 268
Page views in 2019 to date: 125
Cite this page: Jain D. Castleman disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livertumorcastlemansdisease.html. Accessed May 20th, 2019.
Definition / general
  • Uncommon lymphoproliferative disorder involving lymph nodes in one region or systemic
  • Also called angiofollicular hyperplasia
Microscopic (histologic) description
  • Stellate fibrous scar separates small nodules of disorganized large and clear hepatocytes
  • Scar contains hyperplastic follicles with germinal centers, separated by sheets of plasma cells and vessels
  • Small lymphocytes are arranged in onion skin pattern around follicles
Back to top