Liver and intrahepatic bile ducts - tumor
Other malignancies
Germ cell tumors

Author: Deepali Jain, M.D. (see Authors page)

Revised: 1 December 2017, last major update February 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Germ cell tumors[TI] liver

Cite this page: Jain, D. Germ cell tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livertumorgermcelltumors.html. Accessed December 11th, 2017.
Definition / general
  • < 1% of all liver neoplasms, mostly children < 3 years old, 50% are malignant
  • Usually teratoma, choriocarcinoma, yolk sac tumor
  • Teratoma: uncommon, usually girls < 1 year old
Case reports
Gross description
  • Large, cystic, calcified
Gross images

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Teratoma

Microscopic (histologic) description
  • Teratomas: derivatives of all 3 cell layers; often cystic, lined by ectoderm with skin appendages or endoderm; rarely have neuroendocrine differentiation (Histopathology 2003;43:306)
  • May have other liver tumor component (hepatoblastoma)
Microscopic (histologic) images

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Primary mixed germ cell tumor (yolk sac tumor and immature teratoma)

Teratoma

Molecular / cytogenetics images

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Primary mixed
germ cell tumor
(yolk sac tumor and
immature teratoma)