Liver and intrahepatic bile ducts - Tumor

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Liver and intrahepatic bile ducts - Tumor

Benign tumors

Glomangioma

Reviewers: Deepali Jain, M.D. (see Reviewers page)
Revised: 9 January 2013, last major update February 2012
Copyright: (c) 2004-2013, PathologyOutlines.com, Inc.

General
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● Rare, <25 cases reported
● Glomus tumor (neoplasm of glomus apparatus) with prominent vascular structures

Case reports
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● 57 year old man with flank pain and 3 cm liver mass (Arch Pathol Lab Med 2004;128:e46)

Radiology images
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Hypervascular mass

Gross description
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● Well-defined encapsulated tumor mass with dark-red soft cut surface

Micro description
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● Small to medium branched vessels with stroma containing small, round regular cells with sharply outlined round/oval nuclei; low mitotic activity

Micro images
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Small bland tumor cells in vascular network

Smooth muscle actin and CD34

Positive stains
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● Vimentin, smooth muscle actin, CD34, calponin (focal)

Negative stains
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● Desmin, S100, chromogranin, CD117

Differential diagnosis
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● Angiosarcoma: infiltrative, cellular atypia
● Hemangioendothelioma: intracytoplasmic lumina
● Hemangiopericytoma: staghorn vessels

End of Liver and intrahepatic bile ducts - Tumor > Benign tumors > Glomangioma

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