Liver and intrahepatic bile ducts - Tumor - Hepatic vascular malformation with capillary proliferation

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Liver and intrahepatic bile ducts - Tumor

Benign tumors

Hepatic vascular malformation with capillary proliferation

Reviewers: Deepali Jain, M.D. (see Reviewers page)
Revised: 9 January 2013, last major update February 2012
Copyright: (c) 2004-2013, PathologyOutlines.com, Inc.

General
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● Congenital vascular malformation; usually symptomatic at birth
● Does not regress spontaneously
● Symptoms: abdominal mass or distention, cardiomegaly, congestive heart failure, anemia, thrombocytopenia, DIC, fever, jaundice, elevated serum AFP

Treatment
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● Lobectomy; good outcome

Case reports
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● 3 month old girl (Gastroenterology 2011;140:1883)

Gross description
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● Single large mass, mean 8 cm, range 5-11 cm
● Central infarction and hemorrhage is common

Micro description
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● Outer dilated vessels lined by flattened endothelium and loose myxoid stroma
● Central infarction and hemorrhage; bile duct entrapment

Micro images
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Low magnification

Differential diagnosis
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● Infantile hemangioendothelioma: presents after birth; proliferating multifocal lesion followed by spontaneous involution typically composed of only small vessels without central regression; GLUT1+ (Hum Pathol 2004;35:200)

End of Liver and intrahepatic bile ducts - Tumor > Benign tumors > Hepatic vascular malformation with capillary proliferation

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