Liver and intrahepatic bile ducts - tumor
Other malignancies
Hepatoblastoma - mixed epithelial mesenchymal type


Topic Completed: 1 February 2012

Revised: 15 December 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Hepatoblastoma mixed epithelial mesenchymal

Deepali Jain, M.D.
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Cite this page: Jain, D. Hepatoblastoma - mixed epithelial mesenchymal type. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livertumorhepatoblastomamixed.html. Accessed April 9th, 2020.
Definition / general
  • 44% of hepatoblastomas are mixed epithelial mesenchymal type
  • Mixture of fetal / epithelial and mesenchymal cell types
  • Teratoid (34%) or not (10%)
  • Mesenchymal component has spindle oval cells with minimal cytoplasm, frequent osteoid, fibrous septa, myxoid zones, hemorrhage and necrosis
  • Teratoid features are keratinized squamous epithelium, intestinal epithelial, skeletal muscle, mature bone and cartilage, melanin and neuroectodermal structures
Microscopic (histologic) images

Images hosted on other servers:

Mixed pattern

Postchemotherapy treatment effect

Positive stains
Negative stains
Electron microscopy description
  • Immature hepatocytes
Molecular / cytogenetics description
Differential diagnosis
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