Liver and intrahepatic bile ducts - tumor
Other malignancies
Malignant histiocytosis

Author: Deepali Jain, M.D. (see Authors page)

Revised: 4 December 2017, last major update February 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Malignant histiocytosis[TI] liver[TIAB]

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Cite this page: Jain, D. Malignant histiocytosis. website. Accessed January 19th, 2019.
Definition / general
  • Rare neoplasm of abnormal histiocytes typically affecting liver, spleen, lymph nodes, bone marrow
  • Also called histiocytic sarcoma
Microscopic (histologic) description
  • Large cells with multilobed nuclei, abundant eosinophilic cytoplasm and erythrophagocytosis
Microscopic (histologic) images

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Various images (head and neck)

Positive stains