Liver and intrahepatic bile ducts - tumor
Leukemia / lymphoma
Nodal CD8+ cytotoxic peripheral T cell lymphoma



Topic Completed: 1 February 2012

Revised: 28 January 2019, last major update February 2012

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PubMed Search: Nodal CD8+ cytotoxic peripheral T cell lymphoma

See also: Lymphoma and plasma cell neoplasms chapter

Deepali Jain, M.D.
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Page views in 2019 to date: 42
Cite this page: Jain D. Nodal CD8+ cytotoxic peripheral T cell lymphoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livertumornodalcytotoxicperipheralT.html. Accessed July 22nd, 2019.
Definition / general
  • Most peripheral T cell lymphomas are CD4+; CD8+ tumors are rare
  • Associated with disseminated intravascular coagulation (DIC) and hemophagocytic syndrome
  • Poor prognosis
Sites
  • Lymph node (all), liver, bone marrow and CNS
Case reports
Microscopic (histologic) description
  • Neoplastic cells (small to large) with irregular / elongated nucleus with dense chromatin and indistinct nucleoli; also macrophages containing necrotic material
Positive stains
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