Liver and intrahepatic bile ducts - tumor
Leukemia / lymphoma
Nodal CD8+ cytotoxic peripheral T cell lymphoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 30 November 2017, last major update February 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Nodal CD8+ cytotoxic peripheral T cell lymphoma

See also: Lymphoma and plasma cell neoplasms chapter
Cite this page: Jain, D. Nodal CD8+ cytotoxic peripheral T cell lymphoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livertumornodalcytotoxicperipheralT.html. Accessed April 25th, 2018.
Definition / general
  • Most peripheral T cell lymphomas are CD4+; CD8+ tumors are rare
  • Associated with disseminated intravascular coagulation (DIC) and hemophagocytic syndrome
  • Poor prognosis
Sites
  • Lymph node (all), liver, bone marrow and CNS
Case reports
Microscopic (histologic) description
  • Neoplastic cells (small to large) with irregular / elongated nucleus with dense chromatin and indistinct nucleoli; also macrophages containing necrotic material
Positive stains