Liver and intrahepatic bile ducts - tumor
Pleomorphic (giant cell) variant of hepatocellular carcinoma
Reviewers: Deepali Jain, M.D. (see Reviewers page)
Revised: 9 January 2013, last major update February 2012
Copyright: (c) 2004-2013, PathologyOutlines.com, Inc.
● < 1% of all hepatocellular carcinomas, although 15% have some tumor giant cells
● Multinucleated tumor giant cells predominate, marked loss of cell cohesion (Am J Clin Pathol 1990;93:111)
● Infant with syncytial giant cell variant (Ann Diagn Pathol 2007;11:61)
● 50 year old man presenting with atrial metastasis (Indian J Pathol Microbiol 2011;54:632)
Multifocal gray tumor nodules in cirrhotic liver
Pleomorphic tumor giant cells in background of cirrhosis
Pleomorphic tumor giant cells
End of Liver and intrahepatic bile ducts - tumor > Hepatocellular carcinoma > Pleomorphic (giant cell) variant of hepatocellular carcinoma
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).