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Liver and intrahepatic bile ducts - Tumor

Benign tumors

Solitary necrotic nodules

Reviewers: Deepali Jain, M.D. (see Reviewers page)
Revised: 9 January 2013, last major update February 2012
Copyright: (c) 2004-2013, PathologyOutlines.com, Inc.


● <100 cases reported
● May represented sclerosed hemangiomas, prior parasitic infection, trauma, bile duct hamartomas, ischemia
● Usually males, >75% in right lobe, all on hepatic surface (Case Rep Gastroenterol 2008;2:149)
● May regress spontaneously (Hepatol Int 2010; 4:649) or be associated with malignancy (J Gastrointest Surg 2010;14:536)


● Resection

Gross description

● 0.2 to 2.5 cm, single or multiple (more appropriate term is fibrosing necrotic nodule), below anterior border of liver

Micro description

● Hyalinized fibroelastic capsule surrounds necrotic core
● Variable calcification, cholesterol, foam cells, and some inflammatory cells
● AFB and fungal stains negative

Micro images

Various images

End of Liver and intrahepatic bile ducts - Tumor > Benign tumors > Solitary necrotic nodules

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