Liver and intrahepatic bile ducts - nontumor
Vascular disorders

Author: Raul S. Gonzalez, M.D.
Deputy Editor Review: Debra Zynger, M.D.

Revised: 8 March 2018, last major update February 2018

Copyright: (c) 2002-2018,, Inc.

PubMed Search: (Vascular disorders liver [title]) Review[ptyp] "loattrfree full text"[sb]

Cite this page: Gonzalez, R.S. Vascular disorders - general. website. Accessed March 19th, 2018.
Definition / general
  • Vascular disorders affecting the liver can be systemic or localized and have intrinsic or extrinsic causes
  • Intrinsic causes:
  • Extrinsic disorders include heart failure, causing congestive hepatopathy
  • Normal liver is resistant to ischemia, due to dual blood inflow (hepatic artery and portal vein)
  • Cirrhosis also causes vascular remodeling, though it is not generally considered a vascular disorder (J Hepatol 2014;61:912)
Microscopic (histologic) description
  • Inflow abnormalities often cause ischemic necrosis
  • Outflow abnormalities often cause sinusoidal dilation
  • Most other histologic changes depend on the causative disease
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Raul S. Gonzalez, M.D.

Ischemic necrosis

Sinusoidal dilatation