Liver and intrahepatic bile ducts-nontumor
Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 15 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.
● Due to obstruction to inflow (hepatic artery or portal vein) or outflow (central veins, major hepatic veins, inferior vena cava, congestive heart failure) or severe hypotension
● Normal liver is resistant to ischemia due to dual inflow and possibly also collaterals
● Obstruction of outflow causes central passive congestion, leading to hepatocellular atrophy and centrilobular fibrosis that may obliterate central vein lumina
● Causes of outflow obstruction: radiotherapy, alkylating agents, Comfrey tea
End of Liver and intrahepatic bile ducts-nontumor > Vascular disorders > General
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