Liver & intrahepatic bile ducts nontumor
Vascular disorders
Vascular disorders-general

Deputy Editor-in-Chief: Debra Zynger, M.D.
Raul S. Gonzalez, M.D.

Topic Completed: 1 February 2018

Minor changes: 1 July 2020

Revised: 23 January 2019, last major update February 2018

Copyright: (c) 2002-2018,, Inc.

PubMed Search: (Vascular disorders liver [title]) Review[ptyp] "loattrfree full text"[sb]

Raul S. Gonzalez, M.D.
Page views in 2019: 424
Page views in 2020 to date: 247
Cite this page: Gonzalez R. Vascular disorders-general. website. Accessed July 4th, 2020.
Definition / general
  • Vascular disorders affecting the liver can be systemic or localized and have intrinsic or extrinsic causes
  • Intrinsic causes:
  • Extrinsic disorders include heart failure, causing congestive hepatopathy
  • Normal liver is resistant to ischemia, due to dual blood inflow (hepatic artery and portal vein)
  • Cirrhosis also causes vascular remodeling, though it is not generally considered a vascular disorder (J Hepatol 2014;61:912)
Microscopic (histologic) description
  • Inflow abnormalities often cause ischemic necrosis
  • Outflow abnormalities often cause sinusoidal dilation
  • Most other histologic changes depend on the causative disease
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Raul S. Gonzalez, M.D.

Ischemic necrosis

Sinusoidal dilatation

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