Table of ContentsDefinition / general
Cite this page: Arora, K. Vascular disorders - general. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/livervasculargeneral.html. Accessed February 18th, 2018.
Definition / general
- Due to obstruction to inflow (hepatic artery or portal vein) or outflow (central veins, major hepatic veins, inferior vena cava, congestive heart failure) or severe hypotension
- Normal liver is resistant to ischemia due to dual inflow and possibly also collaterals
- Obstruction of outflow causes central passive congestion, leading to hepatocellular atrophy and centrilobular fibrosis that may obliterate central vein lumina
- Causes of outflow obstruction: radiotherapy, alkylating agents, comfrey tea