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Liver and intrahepatic bile ducts-nontumor

Viral hepatitis

General


Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 10 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.

General
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● Infections differ if host is immunocompromised
● Hepatotrophic viruses are A, B, C, delta agent, E, G
● May be self-limiting (hepatitis A), cause chronic liver disease and cirrhosis (hepatitis B and C), cause massive necrosis and acute liver failure (rare with hepatitis C)

Viruses that infect liver and other organs:
● Adenovirus
● Crimean/Congo hemorrhagic fever (Russia, Africa, Pakistan, Iraq, Dubai)
● Ebola (Africa)
● Enteroviruses
● Junin hemorrhagic fever (Argentina)
● Lassa fever (Nigeria)
● Machupo hemorrhagic fever (Bolivia)
● Marburg virus (Uganda green monkeys)
● Measles (rubeola)
● Rift valley fever (Africa)
● Rubella
● Yellow fever

Carrier state:
● Virus present, but either no clinically apparent disease or chronic hepatitis
● Best characterized for hepatitis B
● Present in 90% infected early in life or at childbirth versus 1-10% of adult infections with hepatitis B
● Associated with impaired immunity

End of Liver and intrahepatic bile ducts-nontumor > Viral hepatitis > General


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