Lung - nontumor
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Table of ContentsDefinition / general | Clinical features | Treatment | Gross description | Gross images | Microscopic (histologic) images
Cite this page: Weisenberg E. Abscess. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumorabscess.html. Accessed October 15th, 2019.
Definition / general
- Focal suppurative process characterized by necrosis of lung tissue (eMedicine)
- Due to sinobronchial infections, dental sepsis, aspiration (due to alcoholism, coma, debilitation), primary bacterial infection (Staphylococcus aureus, Klebsiella pneumonia, Streptococcus pneumonia), anaerobic and aerobic streptococci, fungi; anaerobes from the oral cavity (bacteroides, fusobacterium, peptococcus species are the only isolates in 60% of cases), bronchiectasis, post transplant, septic emboli, neoplasia induced obstruction, idiopathic
- Aspiration induced abscesses are more common on right side (right sided bronchus is more vertical), usually single
- Air fluid level present if there is communication with air passages
- Symptoms: cough, fever, copious foul smelling sputum, fever, chest pain, weight loss, clubbing of digits
- 10% of cases are associated with underlying carcinoma
- May extend into pleural cavity and create septic emboli, causing meningitis or brain abscess; serve as nidus for fungal overgrowth (Mucor, aspergillus); may spread elsewhere in lung
- Thick, fibrotic walls in chronic abscesses with adjacent active pneumonia
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