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Lung-nontumor

Infections

Bacillary angiomatosis


Reviewer: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 4 September 2011, last major update September 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Clinical features
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● Mainly occurs in immunodeficient patients, especially in AIDS, but also with transplantation and chemotherapy
● Caused by Bartonella henselae, B. quintana
● Pseudoneoplastic vascular proliferation affecting skin, soft tissue, lungs, bronchi, and other sites; known as peliosis in the liver and spleen
● See also Lymph nodes-not lymphoma chapter

Case report
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● Polypoid endobroncial nodules in HIV+ man (Chest 1992;102:972)

Treatment
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● Erythromycin, other macrolides or doxycycline are very effective

Micro description
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● Vascular proliferation with neutrophils and mononuclear cells with smudgy basophilic material representing bacteria
● Prominent endothelial cells with nuclear atypia and mitotic figures

Micro images
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Lymph node

Positive stains
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● Warthin-Starry, GMS, gram stain (organisms are gram negative)

End of Lung-nontumor > Infections > Bacillary angiomatosis


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