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Lung-nontumor

Pneumoconiosis

Berylliosis


Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 26 September 2011, last major update September 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Due to heavy exposure to dusts or fumes of beryllium, more common in nuclear and aerospace industries
● Acute disease has disappeared due to exposure standards
● Low-dose exposure may cause granulomatous lesions that mimic sarcoidosis
● Chronic berylliosis due to cell-mediated immunity
● 2% of those exposed develop disease; delayed hypersensitivity leads to non-caseating granulomas in lungs and hilar nodes, which become progressively fibrotic; no symptoms until late
● Heavy beryllium exposure is linked to lung cancer

End of Lung-nontumor > Pneumoconiosis > Berylliosis


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