Lung - nontumor
Pneumoconiosis
Berylliosis



Topic Completed: 1 September 2011

Revised: 30 January 2019, last major update September 2011

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PubMed search: pulmonary berylliosis


Elliot Weisenberg, M.D.
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Page views in 2019 to date: 925
Table of Contents
Definition / general
Cite this page: Weisenberg E. Berylliosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumorberylliosis.html. Accessed December 9th, 2019.
Definition / general
  • Due to heavy exposure to dusts or fumes of beryllium, more common in nuclear and aerospace industries
  • Acute disease has disappeared due to exposure standards
  • Low dose exposure may cause granulomatous lesions that mimic sarcoidosis
  • Chronic berylliosis due to cell mediated immunity
  • 2% of those exposed develop disease; delayed hypersensitivity leads to noncaseating granulomas in lungs and hilar nodes, which become progressively fibrotic; no symptoms until late
  • Heavy beryllium exposure is linked to lung cancer
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