Lung - nontumor
Pneumoconiosis
Berylliosis

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 1 March 2017, last major update September 2011

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed search: pulmonary berylliosis

Table of Contents
Definition / general
Cite this page: Berylliosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumorberylliosis.html. Accessed May 1st, 2017.
Definition / general
  • Due to heavy exposure to dusts or fumes of beryllium, more common in nuclear and aerospace industries
  • Acute disease has disappeared due to exposure standards
  • Low dose exposure may cause granulomatous lesions that mimic sarcoidosis
  • Chronic berylliosis due to cell mediated immunity
  • 2% of those exposed develop disease; delayed hypersensitivity leads to noncaseating granulomas in lungs and hilar nodes, which become progressively fibrotic; no symptoms until late
  • Heavy beryllium exposure is linked to lung cancer