Lung - nontumor

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 23 February 2017, last major update September 2011

Copyright: (c) 2003-2017,, Inc.

PubMed search: blastomyces [title] lungs

Cite this page: Blastomyces. website. Accessed December 13th, 2018.
Clinical features
  • See also Skin - nontumor chapter
  • Dimorphic fungus found in soil in Central and Southeastern United States and Canada (bordering Great Lakes, St. Lawrence River, Mississippi River and Ohio River basins), Mexico, Africa, India, Middle East
  • More common in males
  • Due to inhalation of soil containing microfoci of mycelia (Clin Microbiol Rev 2010;23:367)
  • Difficult to isolate in clinical microbiology laboratory
  • May present as consolidative pneumonia, ARDS or nodules resembling carcinoma; prefers upper lobes
  • May also infect skin and bone
  • Grossly often resembles tuberculosis
Microscopic (histologic) description
  • Mixed acute and granulomatous inflammation caused by large budding yeasts (15 - 10 μm) with broad based buds and refractile walls, easily seen with H&E
Microscopic (histologic) images

Images hosted on other servers:

Various images (skin or sputum)