Lung - nontumor
Infections
Blastomyces

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 23 February 2017, last major update September 2011

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed search: blastomyces [title] lungs

Cite this page: Blastomyces. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumorblasto.html. Accessed February 24th, 2017.
Clinical Features
  • See also Skin - nontumor chapter
  • Dimorphic fungus found in soil in Central and Southeastern United States and Canada (bordering Great Lakes, St. Lawrence River, Mississippi River and Ohio River basins), Mexico, Africa, India, Middle East
  • More common in males
  • Due to inhalation of soil containing microfoci of mycelia (Clin Microbiol Rev 2010;23:367)
  • Difficult to isolate in clinical microbiology laboratory
  • May present as consolidative pneumonia, ARDS or nodules resembling carcinoma; prefers upper lobes
  • May also infect skin and bone
  • Grossly often resembles tuberculosis
Micro Description
  • Mixed acute and granulomatous inflammation caused by large budding yeasts (15 - 10 μm) with broad based buds and refractile walls, easily seen with H&E
Micro Images

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Various images (skin or sputum)