Lung-nontumor - Bronchial atresia

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Lung-nontumor

Cystic disease/congenital anomalies

Bronchial atresia

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 25 August 2011, last major update August 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Portion of bronchial tree with normal branching pattern, but without any demonstrable connection to the central bronchial tree
● Congenital abnormality due to focal interruption of lobar, segmental or subsegmental bronchus with associated peripheral mucus impaction (bronchocele, mucocele) and hyperinflation of obstructed lung segment; most commonly affects apicoposterior segmental bronchus of left upper lobe, then segmental bronchi of right upper, middle and lower lobes
● Cause unknown, but appears to occur before birth
● Lobar bronchial atresia can mimic mainstem bronchial atresia on mid-trimester ultrasound (Ultrasound Obstet Gynecol 2011;37:110)

Case reports
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● 22 year old woman with pneumothorax and bronchial atresia (Radiographics 2009;29:1531)

Gross images
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Large bronchocele

Micro images
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Plugged respiratory broncioles and dilated alveoli

End of Lung-nontumor > Cystic disease/congenital anomalies > Bronchial atresia

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