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Lung-nontumor
Cystic disease/congenital anomalies
Bronchogenic cyst
Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 26 August 2011, last major update August 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.
Definition
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● Arises from ectopic foregut; buds of developing embryonic lung become separated from the tracheobronchial tree before bronchi are formed, and may be lined by squamous, ciliated, or columnar epithelium
● May be intrapulmonary or extrapulmonary and are almost always independent of bronchi
● Relatively rare; most common site is posterior mediastinum at level of carina (eMedicine)
● Present as space occupying lesion, may compromise airway
Clinical images
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Translucent round cyst behind the descending aorta
Micro description
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● Lined by respiratory epithelium
Micro images
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Lined by respiratory epithelium
Staining
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● Positive for CK7, negative for CDX2 (Am J Clin Pathol 2008;130:265)
End of Lung-nontumor > Cystic disease/congenital anomalies > Bronchogenic cyst
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