Other interstitial pneumonitis / fibrosis
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 8 October 2013, last major update September 2011
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
- Usually incidental post-mortem finding associated with debilitating disease
- Lipid either exogenous (from nasal sprays or inhalation of other lipid containing substances) or endogenous (bronchial obstruction)
- 71 year old man with recent history of meningitis with recurrent episodes of pneumonia (Case of the Week #287)
- Well-circumscribed, firm with prominent lymphatics on lung surface in exogenous type
Yellow cut surface
- Lipoid material (or empty spaces), inflammatory cells and young fibroblasts
- Reactive endarteritis, marked alveolar lining cell hyperplasia and lipid-laden foamy macrophages
Foamy macrophages in alveolar spaces
End of Lung-nontumor > Other interstitial pneumonitis / fibrosis > Lipoid pneumonia
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