Lung - nontumor
Other interstitial pneumonitis / fibrosis
Lipoid pneumonia

Author: Nat Pernick, M.D. (see Authors page)

Revised: 1 March 2017, last major update September 2011

Copyright: (c) 2002-2017,, Inc.

PubMed search: lipoid pneumonia [title]

Cite this page: Lipoid pneumonia. website. Accessed November 14th, 2018.
Definition / general
  • Usually incidental post mortem finding associated with debilitating disease
  • Lipid either exogenous (from nasal sprays or inhalation of other lipid containing substances) or endogenous (bronchial obstruction)
Case reports
  • 1 year old man with recent history of meningitis with recurrent episodes of pneumonia (Case of the Week #287)
Gross description
  • Well circumscribed, firm with prominent lymphatics on lung surface in exogenous type
Gross images

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Yellow cut surface

Microscopic (histologic) description
  • Lipoid material (or empty spaces), inflammatory cells and young fibroblasts
  • Reactive endarteritis, marked alveolar lining cell hyperplasia and lipid laden foamy macrophages
Microscopic (histologic) images

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Case of Week #287

Case of Week #287

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Aspiration pneumonia

Foamy macrophages in alveolar spaces