Lung - nontumor
Other interstitial pneumonitis / fibrosis
Lipoid pneumonia



Topic Completed: 1 September 2011

Revised: 30 January 2019, last major update September 2011

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PubMed search: lipoid pneumonia [title]


Nat Pernick, M.D.
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Cite this page: Pernick N. Lipoid pneumonia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumorlipoidpneumonia.html. Accessed September 23rd, 2019.
Definition / general
  • Usually incidental post mortem finding associated with debilitating disease
  • Lipid either exogenous (from nasal sprays or inhalation of other lipid containing substances) or endogenous (bronchial obstruction)
Case reports
  • 1 year old man with recent history of meningitis with recurrent episodes of pneumonia (Case of the Week #287)
Gross description
  • Well circumscribed, firm with prominent lymphatics on lung surface in exogenous type
Gross images

Images hosted on other servers:

Yellow cut surface

Microscopic (histologic) description
  • Lipoid material (or empty spaces), inflammatory cells and young fibroblasts
  • Reactive endarteritis, marked alveolar lining cell hyperplasia and lipid laden foamy macrophages
Microscopic (histologic) images

Images hosted on PathOut server:

Case of Week #287


Case of Week #287



Images hosted on other servers:

Aspiration pneumonia

Foamy macrophages in alveolar spaces

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