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Other non-neoplastic disease

Pulmonary alverolar microlithiasis

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 19 December 2011, last major update December 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Clinical features

● Rare, diffuse bilateral microliths or calcospherites with prominent rings within alveoli of otherwise normal lung
● 1/3 of cases are familial, may have autosomal recessive inheritance
● Most cases asymptomatic with benign course, but cough and more severe disease reported
● Microliths may be confused with more common entitity of corpora amylacea
● Microlithiasis is more extensive
● Corpora amylacea may have rings but lack calcification, and examination of Congo red stained material with polarized light reveals a Maltese cross pattern

End of Lung-nontumor > Other non-neoplastic disease > Pulmonary alverolar microlithiasis

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