Lung - nontumor
Other nonneoplastic disease
Pulmonary alveolar microlithiasis



Topic Completed: 1 December 2011

Revised: 30 January 2019, last major update December 2011

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed search: pulmonary alveolar microlithiasis


Elliot Weisenberg, M.D.
Page views in 2018: 434
Page views in 2019 to date: 287
Table of Contents
Clinical features
Cite this page: Weisenberg E. Pulmonary alveolar microlithiasis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumormicrolithiasis.html. Accessed July 20th, 2019.
Clinical features
  • Rare, diffuse bilateral microliths or calcospherites with prominent rings within alveoli of otherwise normal lung
  • 1/3 of cases are familial, may have autosomal recessive inheritance
  • Most cases asymptomatic with benign course, but cough and more severe disease reported
  • Microliths may be confused with more common entity of corpora amylacea
  • Microlithiasis is more extensive
  • Corpora amylacea may have rings but lack calcification, and examination of Congo red stained material with polarized light reveals a Maltese cross pattern
Back to top