Lung - nontumor
Infections
Mycoplasma pneumoniae pneumonia

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 27 February 2017, last major update September 2011

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed search: mycoplasma pneumoniae [title] pneumonia pulmonary

Cite this page: Mycoplasma pneumoniae pneumonia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumormycoplasma.html. Accessed June 27th, 2017.
Definition / general
  • Strict aerobe that lacks a true cell wall, 0.2 - 0.8 μm and among the smallest free living bacterias
  • Formerly called atypical pneumonia (atypical due to moderate sputum production and consolidation and only minimal leukocytosis)
Clinical features
  • Common in children and young adults, but may occur in older age groups
  • Causes community acquired pneumonia (eMedicine), either interstitial (usually) or bronchopneumonia (rare)
  • Often asymptomatic
  • Superimposed bacterial infection may occur
  • Diagnosis: rarely biopsied, diagnose with complement fixation antigen assays; cold agglutinins present in 50% of cases
Treatment
Gross description
  • Reddish blue, congested, patchy lungs; usually no pleuritis
Microscopic (histologic) description
  • Bronchiolitis, interstitial and minimal intra-alveolar involvement with widened alveolar septa due to lymphoplasmacytic inflammatory cells
  • Intra-alveolar proteinaceous material
  • Neutrophilic infiltrate in bronchioles acutely, bronchiolar metaplasia, lymphoplasmacytic infiltrate in bronchial wall and pneumocyte hyperplasia
Electron microscopy images

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EM images

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Gliding phase
Differential diagnosis