Lung - nontumor
Other interstitial pneumonitis / fibrosis
Obliterative bronchiolitis

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 1 March 2017, last major update September 2011

Copyright: (c) 2003-2017,, Inc.

PubMed search: obliterative bronchiolitis [title]

Cite this page: Obliterative bronchiolitis. website. Accessed March 24th, 2018.
Definition / general
  • Associated with bone marrow, heart and lung transplants, rheumatoid arthritis, penicillamine or gold therapy and post viral infection, especially adenovirus
  • Associated with chronic rejection in lung transplant patients, an irreversible condition with poor prognosis
Microscopic (histologic) description
  • May be patchy, fibrosis in submucosa of bronchioles leading to partial or complete occlusion of small airways
  • Inflammatory cell infiltrates may or may not be present
  • Organizing pneumonia may be present
Microscopic (histologic) images

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Follicular bronchiolitis that obliterates lumen