Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 20 October 2014, last major update September 2011
Copyright: (c) 2003-2014, PathologyOutlines.com, Inc.
● Response to infectious or inflammatory injury to the lung
● Pneumonia may resolve or organize
● Organizing pneumonia may simulate malignancy due to radiographic shadows and clinical cough, hemoptysis and weight loss
● May also simulate TB (Pathol Int 2011;61:486)
● Usually due to Streptococcus pneumoniae or Haemophilus influenza
● With subsequent adenocarcinoma (Interact Cardiovasc Thorac Surg 2011 Jul 26 [Epub ahead of print])
● Sharply outlined, firm area with preservation of lung pattern; extends to thickened pleura
● Exudate of fibrin and neutrophils transforming into fibromyxoid masses with histiocytes; may have necrotizing changes in bronchi
Marked interstitial inflammation and granulation tissue in air space; also atypical epithelial proliferation with abundant intracellular mucin (arrowhead).
● Cryptogenic organizing pneumonia (BOOP)
● Inflammatory pseudotumor
End of Lung-nontumor > Infections > Organizing pneumonia
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