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Lung-nontumor

Infections

Organizing pneumonia


Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 21 September 2011, last major update September 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Clinical features
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● Response to infectious or inflammatory injury to the lung
● Pneumonia may resolve or organize
● Organizing pneumonia may simulate malignancy due to radiographic shadows and clinical cough, hemoptysis and weight loss
● May also simulate TB (Pathol Int 2011;61:486)
● Usually due to Streptococcus pneumoniae or Haemophilus influenza

Case reports
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● With subsequent adenocarcinoma (Interact Cardiovasc Thorac Surg 2011 Jul 26 [Epub ahead of print])

Gross description
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● Sharply outlined, firm area with preservation of lung pattern; extends to thickened pleura

Micro description
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● Exudate of fibrin and neutrophils transforming into fibromyxoid masses with histiocytes; may have necrotizing changes in bronchi

Micro images
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Various images


Marked interstitial inflammation and granulation tissue in air space; also atypical epithelial proliferation with abundant intracellular mucin (arrowhead).

Videos
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Organizing pneumonia

Differential Diagnosis
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Cryptogenic organizing pneumonia (BOOP)
Inflammatory pseudotumor

End of Lung-nontumor > Infections > Organizing pneumonia


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