Lung - nontumor - Paragonimus

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Lung-nontumor

Infections

Paragonimus kellicotti

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 21 September 2011, last major update September 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Clinical features
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● Freshwater trematode (lung fluke) found in North America that infects crayfish and crabs as intermediate hosts (MMWR Morb Mortal Wkly Rep 2010;59:1573)
● Humans acquire infection by ingesting raw or undercooked infected shellfish; rarely contaminated seaweed or watercress
● Larvae mature in gut and migrate through diaphragm to infect lungs
● Most cases in Asia due to P. westermani; schistosomiasis may also involve the lung
● May mimic lung tumor (Korean J Parasitol 2011;49:69)
● May require serology to confirm diagnosis

Diagrams
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Life cycle

Case reports
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● 35 year old North American man with recurrent pneumothorax and cavitary lesion (Am J Surg Pathol 2003;27:1157)

Micro description
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● Necrotizing or non-necrotizing granulomas with giant cells containing eggs with operculum; also organizing pneumonia (Am J Surg Pathol 2011;35:707)
● Variable vasculitis and pleuritis; also lymphocytes, plasma cells, eosinophils
● Egg is birefringent

Micro images
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Various images

Cytology images
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Various images

End of Lung-nontumor > Infections > Paragonimus

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