Lung-nontumor - Sequestrations (intralobar and extrapulmonary lobar)

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Lung-nontumor

Cystic disease/congenital anomalies

Sequestrations (intralobar and extrapulmonary lobar)

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 25 August 2011, last major update August 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Lobes or segments of lung without a normal connection to the airway system (eMedicine)
● Arterial blood supply is from aortic branches, NOT pulmonary arteries
● Extrapulmonary sequestrations: external to lung, covered with separate pleural lining, may be anywhere in thorax or mediastinum; usually infants; abnormal masses, 90% on left side, 20% have other congenital anomalies; associated with polyhydramnios and edema; Venous drainage is into azygous system (Ultrasound Obstet Gynecol 2006;27:214)
● Intralobar sequestrations: within the lung, usually lower lobe, segment is supplied by a large artery from aorta, not invested with its own pleura; associated with infections: bronchiectasis, chronic inflammation, and fibrosis; venous drainage is into pulmonary vein

Case reports
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● 25 year old man with mediastinal mass (Ann Thorac Surg 1997;63:1169)

Gross images
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Various images

Micro images
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Various images

End of Lung-nontumor > Cystic disease/congenital anomalies > Sequestrations (intralobar and extrapulmonary lobar)

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