Lung - nontumor
Infections
Tropical pulmonary eosinophilia

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 28 February 2017, last major update September 2011

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed search: tropical pulmonary eosinophilia [title]

Cite this page: Tropical pulmonary eosinophilia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumortropeosin.html. Accessed November 21st, 2017.
Definition / general
  • Due to microfilaria of Wuchereria bancrofti or Brugia malayi, which circulate in pulmonary capillaries and cause an immediate type of eosinophilic hypersensitivity reaction
  • Patients have high levels of IgE and high titers of filarial antibodies
  • Adult worms not seen in lungs
  • Restricted to tropical regions
  • Tropical eosinophilia may occur from filaria in lymph nodes or spleen (Meyers-Kouwenaar syndrome)
  • Symptoms and signs: cough, typically nocturnal, dypsnea, chest tightness, wheezing, fevers, weight loss and eosinophilia
Microscopic (histologic) description
  • Rare microfilaria within pulmonary capillaries with marked eosinophilic infiltrate
  • Eosinophilic abscesses develop into granulomata