Tropical pulmonary eosinophilia
Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 23 September 2011, last major update September 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.
● Due to microfilaria of Wuchereria bancrofti or Brugia malayi, which circulate in pulmonary capillaries and cause an immediate type of eosinophilic hypersensitivity reaction
● Patients have high levels of IgE and high titers of filarial antibodies
● Adult worms not seen in lungs
● Restricted to tropical regions
● Tropical eosinophilia may occur from filaria in lymph nodes or spleen (Meyers-Kouwenaar syndrome)
● Symptoms and signs: cough, typically nocturnal, dypsnea, chest tightness, wheezing, fevers, weight loss and eosinophilia
● Rare microfilaria within pulmonary capillaries with marked eosinophilic infiltrate
● Eosinophilic abscesses develop into granulomata
End of Lung-nontumor > Infections > Tropical pulmonary eosinophilia
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