Lung - nontumor
Tropical pulmonary eosinophilia

Topic Completed: 1 September 2011

Revised: 29 January 2019, last major update September 2011

Copyright: (c) 2003-2017,, Inc.

PubMed search: tropical pulmonary eosinophilia [title]

Elliot Weisenberg, M.D.
Page views in 2019: 275
Page views in 2020 to date: 139
Cite this page: Weisenberg E. Tropical pulmonary eosinophilia. website. Accessed May 28th, 2020.
Definition / general
  • Due to microfilaria of Wuchereria bancrofti or Brugia malayi, which circulate in pulmonary capillaries and cause an immediate type of eosinophilic hypersensitivity reaction
  • Patients have high levels of IgE and high titers of filarial antibodies
  • Adult worms not seen in lungs
  • Restricted to tropical regions
  • Tropical eosinophilia may occur from filaria in lymph nodes or spleen (Meyers-Kouwenaar syndrome)
  • Symptoms and signs: cough, typically nocturnal, dypsnea, chest tightness, wheezing, fevers, weight loss and eosinophilia
Microscopic (histologic) description
  • Rare microfilaria within pulmonary capillaries with marked eosinophilic infiltrate
  • Eosinophilic abscesses develop into granulomata
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