Lymphoma and lymphoid infiltrates
Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 22 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Lymphoma of Bronchus Associated Lymphoid Tissue
● Rare type of low-grade, primary pulmonary MALT lymphoma
● Often need gene rearrangement studies to diagnose
● Indolent with good prognosis
● 41 year old woman with clonality by gene rearrangement but not by flow cytometry
(Arch Pathol Lab Med 2003;127:115)
● Centrocyte-like lymphocytic proliferation in bronchiolar submucosa with lymphoepithelial lesions, reactive lymphocytes and plasma cells
● Bland appearance
H&E with lymphoepithelial lesions
● Reactive hyperplasia
End of Lung tumor > Lymphoma and lymphoid infiltrates > BALT lymphoma
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