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Lung tumor

Lymphoma and lymphoid infiltrates

Hodgkin lymphoma

Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 22 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Very rare (<100 cases reported) as primary tumor of lung; secondary involvement more common
● By definition, primary lung disease is restricted to lung with no involvement of hilar nodes
● Usually good prognosis, but fatal cases occur

Case reports
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● 21 year old woman with localized consolidation (Arch Pathol Lab Med 2003;127:e49)

Gross description
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● Nodular or multinodular lesions in upper lung

Micro description
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● Typical Reed-Sternberg cells, mononuclear cells, lacunar variants in background of mixed inflammatory infiltrate
● Rarely granulomatous inflammation simulating tuberculosis

Micro images
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Figure 3A: CD15; Figure 3B: CD30

Positive stains
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● CD15, CD30

Negative stains
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● Reed-Sternberg like cells: CD45, CD20, CD3, EMA

Differential diagnosis
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● Anaplastic lymphoma
● Organizing pneumonia
● T cell lymphoma
● Tuberculosis
● Wegener’s granulomatosis

End of Lung tumor > Lymphoma and lymphoid infiltrates > Hodgkin lymphoma

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