Lung tumor
Lymphoma and lymphoid infiltrates
Hodgkin lymphoma

Topic Completed: 1 September 2012

Revised: 31 January 2019, last major update September 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Hodgkin lymphoma[title] lung

Deepali Jain, M.D.
Page views in 2018: 249
Page views in 2019 to date: 113
Cite this page: Jain D. Hodgkin lymphoma. website. Accessed June 25th, 2019.
Definition / general
  • Very rare (< 100 cases reported) as primary tumor of lung; secondary involvement more common
  • By definition, primary lung disease is restricted to lung with no involvement of hilar nodes
  • Usually good prognosis, but fatal cases occur
Case reports
Gross description
  • Nodular or multinodular lesions in upper lung
Microscopic (histologic) description
  • Typical Reed-Sternberg cells, mononuclear cells, lacunar variants in background of mixed inflammatory infiltrate
  • Rarely granulomatous inflammation simulating tuberculosis
Microscopic (histologic) images

Images hosted on other servers:

Fig 3A: CD15; Fig 3B: CD30

Positive stains
  • CD15, CD30
Negative stains
  • Reed-Sternberg like cells: CD45, CD20, CD3, EMA
Differential diagnosis
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