Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Lung tumor

Lymphoma and lymphoid infiltrates

Hodgkin lymphoma


Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 22 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
=========================================================================

● Very rare (<100 cases reported) as primary tumor of lung; secondary involvement more common
● By definition, primary lung disease is restricted to lung with no involvement of hilar nodes
● Usually good prognosis, but fatal cases occur

Case reports
=========================================================================

● 21 year old woman with localized consolidation (Arch Pathol Lab Med 2003;127:e49)

Gross description
=========================================================================

● Nodular or multinodular lesions in upper lung

Micro description
=========================================================================

● Typical Reed-Sternberg cells, mononuclear cells, lacunar variants in background of mixed inflammatory infiltrate
● Rarely granulomatous inflammation simulating tuberculosis

Micro images
=========================================================================



Figure 3A: CD15; Figure 3B: CD30

Positive stains
=========================================================================

● CD15, CD30

Negative stains
=========================================================================

● Reed-Sternberg like cells: CD45, CD20, CD3, EMA

Differential diagnosis
=========================================================================

● Anaplastic lymphoma
Organizing pneumonia
● T cell lymphoma
Tuberculosis
Wegener’s granulomatosis

End of Lung tumor > Lymphoma and lymphoid infiltrates > Hodgkin lymphoma


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).