Lung tumor
Lymphoma and lymphoid infiltrates
CLL / SLL




Topic Completed: 1 September 2012

Revised: 26 March 2019

Revised: 31 January 2019, last major update September 2012

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PubMed Search: chronic lymphocytic leukemia / small lymphocytic lymphoma
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Cite this page: Jain D. CLL / SLL. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungtumorSLLCLL.html. Accessed April 18th, 2019.
Definition / general
  • Chronic lymphocytic leukemia / small lymphocytic lymphoma
  • Usually asymptomatic pulmonary nodules or infiltrates in elderly
  • Involves the lung at autopsy in 30% of cases, may cause significant pulmonary impairment
Gross description
  • Well defined, encapsulated mass, homogenous gray cut surface
Microscopic (histologic) description
  • Monomorphic low grade lymphocytic infiltrate with pseudofollicles
Differential diagnosis
  • Reactive lymphoid infiltrate: polymorphic lymphocytes, germinal centers, other inflammatory cells
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