Lung tumor
Lymphohistiocytic
CLL / SLL


Topic Completed: 1 September 2012

Revised: 22 October 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: chronic lymphocytic leukemia / small lymphocytic lymphoma

Deepali Jain, M.D.
Page views in 2018: 548
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Cite this page: Jain D. CLL / SLL. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungtumorSLLCLL.html. Accessed November 15th, 2019.
Definition / general
  • Chronic lymphocytic leukemia / small lymphocytic lymphoma
  • Usually asymptomatic pulmonary nodules or infiltrates in elderly
  • Involves the lung at autopsy in 30% of cases, may cause significant pulmonary impairment
Gross description
  • Well defined, encapsulated mass, homogenous gray cut surface
Microscopic (histologic) description
  • Monomorphic low grade lymphocytic infiltrate with pseudofollicles
Differential diagnosis
  • Reactive lymphoid infiltrate: polymorphic lymphocytes, germinal centers, other inflammatory cells
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