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Lung tumor

Other carcinoma

Adenosquamous carcinoma


Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 10 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Substantial amounts of squamous and glandular differentiation (at least 5-10% each component of entire tumor)
● Donít diagnose if one component is clearly minor
● Uncommon; <10% of lung carcinomas
● 90% peripheral, often associated with scars
● Metastases may have different histology
● Poorer prognosis than either component alone

Micro images
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Various images

Positive stains
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● TTF1 in adenocarcinoma component and p63 in squamous component (Pathol Int 2011;61:717)

Molecular images
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With KRas and EGFR mutations

End of Lung tumor > Other carcinoma > Adenosquamous carcinoma


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