Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 10 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Presents as mass or diffuse pulmonary infiltrates, usually in adult men (Ann Diagn Pathol 2010;14:296)
● Almost all cases in lung represent metastatic disease
● 83 year old man with epithelioid tumor of lungs (Arch Pathol Lab Med 2005;129:e7)
● Diffusely hemorrhagic lungs with multiple dark red nodules
● Involves interlobar septa and bronchovascular bundles
● Grows along lymphatics or venous routes
Metastatic tumor at autopsy has multiple cystic nodules
Primary angiosarcoma of lung shows (left to right): interanastomosing vascular spaces, tumor cells with atypia and hobnailing that dissect vascular spaces, solid sheets of epithelioid cells, primitive vessel formation
Primary epithelioid (left) and metastatic (right) disease
Post Lucite plombage treatment of pulmonary TB
● Metastatic angiosarcoma
End of Lung tumor > Other malignancies > Angiosarcoma
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