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Lung tumor

Other malignancies

Angiosarcoma


Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 10 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Presents as mass or diffuse pulmonary infiltrates, usually in adult men (Ann Diagn Pathol 2010;14:296)
● Almost all cases in lung represent metastatic disease

Case reports
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● 83 year old man with epithelioid tumor of lungs (Arch Pathol Lab Med 2005;129:e7)

Gross description
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● Diffusely hemorrhagic lungs with multiple dark red nodules
● Involves interlobar septa and bronchovascular bundles
● Grows along lymphatics or venous routes

Gross images
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Metastatic tumor at autopsy has multiple cystic nodules

Micro images
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Primary angiosarcoma of lung shows (left to right): interanastomosing vascular spaces, tumor cells with atypia and hobnailing that dissect vascular spaces, solid sheets of epithelioid cells, primitive vessel formation


Primary epithelioid (left) and metastatic (right) disease


Post Lucite plombage treatment of pulmonary TB

Differential diagnosis
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● Metastatic angiosarcoma

End of Lung tumor > Other malignancies > Angiosarcoma


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