Lung tumor

Topic Completed: 1 September 2012

Revised: 23 October 2019

Copyright: 2003-2019,, Inc.

PubMed Search: pulmonary angiosarcoma

Deepali Jain, M.D.
Page views in 2019: 499
Page views in 2020 to date: 40
Cite this page: Jain D. Angiosarcoma. website. Accessed January 22nd, 2020.
Definition / general
  • Presents as mass or diffuse pulmonary infiltrates, usually in adult men (Ann Diagn Pathol 2010;14:296)
  • Almost all cases in lung represent metastatic disease
Case reports
Gross description
  • Diffusely hemorrhagic lungs with multiple dark red nodules
  • Involves interlobar septa and bronchovascular bundles
  • Grows along lymphatics or venous routes
Gross images

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Metastatic tumor at autopsy has multiple cystic nodules

Microscopic (histologic) images

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Primary angiosarcoma of lung shows (left to right): interanastomosing vascular spaces, tumor cells with atypia and hobnailing that dissect vascular spaces, solid sheets of epithelioid cells, primitive vessel formation

Primary epithelioid (left) and metastatic (right) disease

Differential diagnosis
  • Metastatic angiosarcoma
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