Lung
Neuroendocrine tumors
Atypical carcinoid


Topic Completed: 1 September 2012

Minor changes: 15 October 2020

Copyright: 2003-2020, PathologyOutlines.com, Inc.

PubMed Search: Atypical carcinoid[TI] lung

Deepali Jain, M.D.
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Cite this page: Jain D. Atypical carcinoid. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungtumoratypicalcarcinoid.html. Accessed October 20th, 2020.
Definition / general
  • Also called moderately differentiated neuroendocrine carcinoma
  • Diagnostic criteria (Rosai): resembles a carcinoid but with atypical features
  • More aggressive than typical carcinoid tumors: nodal metastases in 70% vs. 5%
  • 5 year survival is 49-69%
Microscopic (histologic) description
  • Carcinoid tumors with increased mitotic activity (2-10 per 10 HPF), nuclear pleomorphism or foci of necrosis
Microscopic (histologic) images

Contributed by Yale Rosen, M.D.
Atypical carcinoid tumor of lung metastatic to adrenal gland Atypical carcinoid tumor of lung metastatic to adrenal gland Atypical carcinoid tumor of lung metastatic to adrenal gland Atypical carcinoid tumor of lung metastatic to adrenal gland

Atypical carcinoid tumor of lung metastatic to adrenal gland



Images hosted on other servers:
Various images Various images Various images

Various images

Various immunostains with various tumors

Various immunostains with various tumors

Positive stains
Negative stains
Electron microscopy description
  • Numerous large neurosecretory granules
Differential diagnosis
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