Lung tumor
Other
Cytology

Author: Deepali Jain, M.D. (see Authors page)

Revised: 19 July 2018, last major update September 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: cytology lung carcinoma
Table of Contents
Definition / general
Cite this page: Jain, D. Cytology. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungtumorcytology.html. Accessed October 15th, 2018.
Definition / general
  • Sputum or bronchial brushings are 80 - 90% sensitive for lung carcinoma if examine 5+ sputum samples
  • Fine needle aspirate is superior to bronchoalveolar lavage for diagnosis of pathologic pathology (Mod Pathol 2002;15:1259)
  • False positives: due to misidentification of macrophages or pneumocytes - includes bronchiectasis, fungal infections, infarct, lipoid pneumonia, post-radiation changes, viral pneumonia
  • False negatives: often due to sampling (Diagn Cytopathol 2012;40:556); pleural fluid cytology is often falsely negative for small cell carcinoma
  • Also useful for mutation analysis (Acta Cytol 2012;56:661)