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Lung tumor

Lymphoma and lymphoid infiltrates

Diffuse large B cell lymphoma


Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 22 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Presents as large parenchymal mass accompanied by necrosis, occasionally by intrabronchial mass
● May evolve from MALT lymphoma or arise without preexisting lesions
● 5 year survival is 50%

Micro description
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● Pleomorphic large lymphoid cells, usually noncleaved
● Various patterns of infiltration (Am J Clin Pathol 2004;121:718)

Positive stains
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● CD20

Negative stains
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● CD3, CD5, CD26

End of Lung tumor > Lymphoma and lymphoid infiltrates > Diffuse large B cell lymphoma


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