Lung tumor
Other carcinoma
Epithelial-myoepithelial carcinoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 22 December 2016, last major update September 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Epithelial-myoepithelial carcinoma lung
Cite this page: Epithelial-myoepithelial carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungtumorepithelialmyo.html. Accessed May 26th, 2017.
Definition / general
  • Low grade malignancy that arises from submucosal bronchial glands, mimics similar salivary gland tumor
  • Very rare, < 20 cases reported through 2009
  • Ages 40-69 years
  • Long interval to recurrence or metastasis
Case reports
Gross description
  • Intraluminal polypoid mass in bronchus; may invade pulmonary parenchyma
Gross images

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Incidental endobronchial mass

Microscopic (histologic) description
  • Well circumscribed mass, pushing margin
  • Biphasic proliferation of epithelial and myoepithelial cells with formation of bilayered ductlike structures
  • Tumor consists of ductlike structures with inner epithelial cells and outer clear myoepithelial cells
  • No myxoid / chondroid stroma, no perineural invasion (Hum Pathol 2009;40:366)
Microscopic (histologic) images

Images hosted on PathOut server:

Case of the Week #357:

Lung biopsy



Images hosted on other servers:

Various images



Incidental endobronchial mass:

H&E

Calponin

S-100


AE1/AE3

CK7

CK903

Ki-67

Positive stains
Negative stains
Differential diagnosis