Table of ContentsDefinition / General | Case Reports | Gross Images | Micro Description | Micro Images | Positive Stains
Cite this page: Giant cell carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungtumorgiantcellcarcinoma.html. Accessed April 26th, 2017.
Definition / General
- Neoplastic, highly pleomorphic giant cells, often in inflammatory stroma with emperipolesis (Arch Pathol Lab Med 2010;134:1645)
- Giant cells are multinucleated, may resemble syncytiotrophoblasts and produce human chorionic gonadotropin, but are usually fewer than in primary choriocarcinoma of lung (Histopathology 2000;36:17)
- No sarcomatoid component present
- Calretinin (67%)