Metastatic endometrial stromal sarcoma
Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 12 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Metastases to lung are rare; occur a mean 10 years after diagnosis of uterine tumor
● Excellent prognosis - patients only rarely die of disease (Am J Surg Pathol 2002;26:440, Am J Surg Pathol 2002;26:1142)
● Note: uterine diagnosis often not disclosed to pathologist
● Well circumscribed, solid tumor composed of plump spindle cells in short fascicles, often with hyalinized areas
● May have cystic or sex cord-like areas
● Vimentin, ER, PR, CD10
● Variable smooth muscle actin, desmin and keratin
● Chromogranin, HMB45
● Carcinoid tumor
● Sclerosing hemangioma
End of Lung tumor > Other carcinoma > Metastatic endometrial stromal sarcoma
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