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Lung tumor

Other Carcinoma

Metastatic endometrial stromal sarcoma

Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 12 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Metastases to lung are rare; occur a mean 10 years after diagnosis of uterine tumor
● Excellent prognosis - patients only rarely die of disease (Am J Surg Pathol 2002;26:440, Am J Surg Pathol 2002;26:1142)
● Note: uterine diagnosis often not disclosed to pathologist

Micro description
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● Well circumscribed, solid tumor composed of plump spindle cells in short fascicles, often with hyalinized areas
● May have cystic or sex cord-like areas

Micro images
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Various images

Positive stains
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● Vimentin, ER, PR, CD10
● Variable smooth muscle actin, desmin and keratin

Negative stains
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● Chromogranin, HMB45

Differential diagnosis
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● Carcinoid tumor
● Endometriosis
● Hemangiopericytoma
● Lymphangioleiomyomatosis
● Lymphoma
● Sclerosing hemangioma

End of Lung tumor > Other carcinoma > Metastatic endometrial stromal sarcoma

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