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Lung tumor

Other Carcinoma

Mucoepidermoid carcinoma

Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 12 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Low grade or high grade salivary gland type tumor with mucus secreting cells, squamous cells, intermediate type cells
● May arise from submucous bronchial glands, usually in large bronchi
● May occur in children
● Usually considered to have low malignant potential with recurrence but only rarely aggressive
● Excellent prognosis after surgical removal

Case reports
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● 22 year old man (Diagn Pathol 2012 Oct 8;7:137)

Gross description
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● Polypoid growth in major bronchi

Micro description
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● Low grade or high grade
● Mucus secreting cells, squamous cells, intermediate type cells
● May have dense lymphoplasmacytic infiltrate (Am J Surg Pathol 2005;29:407)

Micro images
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Various images

 
Series of images - high grade tumor

     
Series of images - low grade tumor

Positive stains
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● Cyclin D1 overexpression in 20%

Differential diagnosis
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● Adenosquamous carcinoma: usually peripheral in lung, not centered on bronchi; large tumors, no intermediate cells

End of Lung tumor > Other carcinoma > Mucoepidermoid carcinoma

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