Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 12 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Low grade or high grade salivary gland type tumor with mucus secreting cells, squamous cells, intermediate type cells
● May arise from submucous bronchial glands, usually in large bronchi
● May occur in children
● Usually considered to have low malignant potential with recurrence but only rarely aggressive
● Excellent prognosis after surgical removal
● 22 year old man (Diagn Pathol 2012 Oct 8;7:137)
● Polypoid growth in major bronchi
● Low grade or high grade
● Mucus secreting cells, squamous cells, intermediate type cells
● May have dense lymphoplasmacytic infiltrate (Am J Surg Pathol 2005;29:407)
Series of images - high grade tumor
Series of images - low grade tumor
● Cyclin D1 overexpression in 20%
● Adenosquamous carcinoma: usually peripheral in lung, not centered on bronchi; large tumors, no intermediate cells
End of Lung tumor > Other carcinoma > Mucoepidermoid carcinoma
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