Lung tumor - Squamous papilloma

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Lung tumor

Benign tumors

Squamous papilloma

Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 8 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Papillomas are HPV related benign tumors, uncommon in lower bronchial tree
● 3 types: squamous, glandular, mixed (Am J Surg Pathol 1998;22:1328)
● Usually occur in large bronchi, often with associated tracheal or laryngeal lesions
● Often associated with dysplasia, carcinoma in situ or invasive squamous cell carcinoma

Case reports
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● 42 year old woman (Kyobu Geka 2012;65:808)
● 70 year old man with spindle and squamous cell carcinoma arising in peripheral mixed squamous and glandular papilloma (Arch Pathol Lab Med 2011;135:1353)
● 79 year old woman with HPV11 in tumor (Intern Med 1999;38:817)

Micro images
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23 year old nonsmoking woman

Micro description
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● Papillary lesion covered by squamous epithelium; may contain glandular areas (with mucus)

Micro images
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Various images

Pulmonary inverted schneiderian papilloma

Differential diagnosis
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● Mucoepidermoid carcinoma: for papillomas with mucus cells

End of Lung tumor > Benign tumors > Squamous papilloma

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