Lymph nodes - not lymphoma
Follicular dendritic cells

Author: William D. DePond, M.D. (see Authors page)

Revised: 20 June 2018, last major update June 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Follicular dendritic cells [title] lymph nodes [title]

Related Topics: Accessory immune system

Page views in 2018: 130
Page views in 2019 to date: 366
Cite this page: DePond, W. D. Normal: follicular dendritic cells. website. Accessed November 15th, 2019.
Definition / general
  • Associated with germinal centers
  • Have complex cell processes joined by desmosomes, but no Birbeck granules
  • Control B cell maturation and isotype switching
  • FDC like cells can be produced from monocytes (BMC Immunol 2005;6:23)
  • Upregulated by Tamoxifin treatment for breast cancer (Am J Pathol 2003;163:1313)
Positive stains
Negative stains
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