Lymph nodes - not lymphoma
Normal
Follicular dendritic cells

Author: William D. DePond, M.D. (see Authors page)

Revised: 20 June 2018, last major update June 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Follicular dendritic cells [title] lymph nodes [title]

Related Topics: Accessory immune system

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Cite this page: DePond, W. D. Normal: follicular dendritic cells. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesaccessoryimmunefollicular.html. Accessed November 15th, 2019.
Definition / general
  • Associated with germinal centers
  • Have complex cell processes joined by desmosomes, but no Birbeck granules
  • Control B cell maturation and isotype switching
  • FDC like cells can be produced from monocytes (BMC Immunol 2005;6:23)
  • Upregulated by Tamoxifin treatment for breast cancer (Am J Pathol 2003;163:1313)
Positive stains
Negative stains
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