Lymph nodes - not lymphoma
Normal
Macrophages


Topic Completed: 1 June 2013

Revised: 15 December 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Macrophages [title] lymph nodes [title]

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Cite this page: DePond, W. D. Macrophages. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesaccessoryimmunemacrophages.html. Accessed January 18th, 2020.
Definition / general
  • Process antigens via phagocytosis
  • Related to circulatory monocytes
  • Are present throughout the lymph node
  • May contain thyroglobulin in lymph nodes draining thyroid tumors (J Clin Pathol 2001;54:314)
Microscopic (histologic) description
  • Abundant cytoplasm with medium to large nuclei with vesicular chromatin
  • Tingible body macrophages have clear cytoplasm and contain apoptotic bodies, which gives node a starry sky pattern
Microscopic (histologic) images

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Macrophages (with pigment) and plasma cells

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Thyroglobulin+ histiocytes

Positive stains
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