Lymph nodes - not lymphoma

Author: William D. DePond, M.D. (see Authors page)

Revised: 20 June 2018, last major update June 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Macrophages [title] lymph nodes [title]

Related Topics: Accessory immune system

Page views in 2018: 299
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Cite this page: DePond, W. D. Normal: macrophages. website. Accessed November 19th, 2019.
Definition / general
  • Process antigens via phagocytosis
  • Related to circulatory monocytes
  • Are present throughout the lymph node
  • May contain thyroglobulin in lymph nodes draining thyroid tumors (J Clin Pathol 2001;54:314)
Microscopic (histologic) description
  • Abundant cytoplasm with medium to large nuclei with vesicular chromatin
  • Tingible body macrophages have clear cytoplasm and contain apoptotic bodies, which gives node a starry sky pattern
Microscopic (histologic) images

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Macrophages (with pigment) and plasma cells

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Thyroglobulin+ histiocytes

Positive stains
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