Lymph nodes - not lymphoma
Neoplasms (not lymphoma)
Angiosarcoma




Topic Completed: 1 January 2014

Revised: 5 February 2019

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PubMed Search: Angiosarcoma lymph nodes

Page views in 2018: 292
Page views in 2019 to date: 181
Cite this page: Tsang P. Angiosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesangiosarcoma.html. Accessed June 17th, 2019.
Definition / general
  • Almost always represents metastatic disease to lymph node
  • May represent regional or distant metastasis
  • Originates from malignant endothelial cells
Clinical features
  • Nodal metastasis reported in 13.5% of angiosarcomas (Ann Surg 1993;217:72)
  • Incidence of nodal spread is relatively high compared to other sarcoma types
  • Aggressive tumor with poor prognosis
Case reports
Treatment
  • Radical lymphadenectomy for isolated regional metastasis
Microscopic (histologic) description
  • Anastomosing vascular channels lined by anaplastic tumor cells
  • May be papillary
  • Infiltrative borders
Microscopic (histologic) images

Images hosted on PathOut server:

Metastatic to lymph node



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Breast

Positive stains
Negative stains
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