Lymph nodes - not lymphoma
Neoplasms (not lymphoma)

Author: Patricia Tsang, M.D. (see Authors page)

Revised: 26 June 2018, last major update January 2014

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Angiosarcoma lymph nodes

Cite this page: Tsang, P. Angiosarcoma. website. Accessed December 12th, 2018.
Definition / general
  • Almost always represents metastatic disease to lymph node
  • May represent regional or distant metastasis
  • Originates from malignant endothelial cells
Clinical features
  • Nodal metastasis reported in 13.5% of angiosarcomas (Ann Surg 1993;217:72)
  • Incidence of nodal spread is relatively high compared to other sarcoma types
  • Aggressive tumor with poor prognosis
Case reports
  • Radical lymphadenectomy for isolated regional metastasis
Microscopic (histologic) description
  • Anastomosing vascular channels lined by anaplastic tumor cells
  • May be papillary
  • Infiltrative borders
Microscopic (histologic) images

Images hosted on PathOut server:

Metastatic to lymph node

Images hosted on other servers:


Positive stains
Negative stains