Lymph nodes - not lymphoma
Inclusions, pigment, ectopic cells or tissue
Asbestos


Senior Author: Abdelsalam Sharabi, M.D.
Jayalakshmi Balakrishna, M.D.

Topic Completed: 1 February 2014

Revised: 1 February 2019, last major update February 2014

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Asbestos [title] lymph nodes


Jayalakshmi Balakrishna, M.D.
Page views in 2018: 253
Page views in 2019 to date: 295
Cite this page: Balakrishna J. Asbestos. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesasbestosbodies.html. Accessed December 7th, 2019.
Terminology
  • Also called Ferruginous bodies
Epidemiology
  • Usually due to industrial / occupational exposure
Sites
  • Most common in thoracic / hilar lymph nodes
  • Concentration of asbestos fibers in lymph nodes is 2 - 3x higher than in lung
Clinical features
  • Inhaled asbestos fibers have iron protein-mucopolysaccharide coating
  • Enlarged lymph nodes are common
  • Associated symptoms / signs of pulmonary asbestosis
Diagnosis
  • Biopsy of affected lymph node
  • Bleach digestion for confirmation
Radiology description
  • Mediastinal / hilar lymphadenopathy
Prognostic factors
  • Pulmonary asbestosis is a risk factor for lung carcinoma and mesothelioma
Case reports
Clinical images

Images hosted on other servers:

Asbestos with mesothelioma
Missing Image

Enlarged supraclavicular node

Missing Image

Epiphrenic node on right

Missing Image

Node inside lesion

Gross description
  • Lymph nodes may be enlarged but show no significant abnormalities on cut surface
Microscopic (histologic) description
  • Asbestos bodies are golden-brown, beaded, or dumbbell shaped structures with a thin, translucent core
Microscopic (histologic) images

Images hosted on other servers:
Missing Image

Asbestos bodies - BAL fluid

Missing Image

Pseudoasbestos bodies

Differential diagnosis
  • Pseudoasbestos bodies
  • Other ferruginous bodies
Back to top