Lymph nodes - not lymphoma
Infectious / parasitic disorders
Brucellosis

Author: William D. DePond, M.D. (see Authors page)

Revised: 29 June 2018, last major update July 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Brucellosis [title] lymph nodes

Cite this page: DePond, W. D. Brucellosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesbrucellosis.html. Accessed August 17th, 2018.
Definition / general
  • Due to Brucella abortus, melitensis or suis
  • Either occupational or food related (milk and cheese)
  • Fever, hepatosplenomegaly, rarely lymphadenopathy
Case reports
  • 22 year old woman with Kikuchi-Fujimoto necrotizing lymphadenitis associated with brucellosis (Sangre (Barc) 1992;37:201)
  • 43 year old man with B. melitensis and subsequent Kikuchi-Fujimoto disease (In Vivo 2003;17:51)
Diagnosis
  • Culture, PCR, serology
Microscopic (histologic) description
  • Follicular hyperplasia, clusters of epithelioid histiocytes that may form large noncaseating granulomas
  • Eosinophils, plasma cells, immunoblasts
Differential diagnosis