Lymph nodes - not lymphoma
Infectious / parasitic disorders
Coccidioides immitis



Topic Completed: 1 June 2013

Revised: 1 February 2019, last major update June 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Coccidioides immitis [title] lymph nodes


William D. DePond, M.D.
Page views in 2018: 189
Page views in 2019 to date: 375
Cite this page: DePond W. Coccidioides immitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodescoccidiodes.html. Accessed June 24th, 2019.
Definition / general
  • Also called San Jaquin Valley Fever
  • Dimorphic fungus with distinct yeast and mold stages
  • Endemic to Lower Sonoran Desert (southwest US, Central and South America)
  • Usually self limiting, but more severe disease in immunocompromised hosts
Case reports
Diagnosis
  • Culture (grows on all media)
  • Has enteroarthric conidia (alternating segments of hyphae undergo autolysis, while surviving segments form infective barrel shaped multinucleate arthroconidia)
Microscopic (histologic) description
  • Thick walled spherules 20 - 150 microns containing 3 - 5 micron endospores, surrounded by a giant cell granulomatous reaction
Microscopic (histologic) images

Images hosted on other servers:
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Figure 1: CT scan
2: H&E shows spherules filled with endospores
3: wooly white mold on blood agar plate after 5 days
4: Lacto-phenol cotton blue stain shows characteristic
enteroarthric conidia formation




Not necessarily lymph node
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Large spherules

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Various images

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