Lymph nodes - not lymphoma
Infectious / parasitic disorders
Severe chronic active EBV infection

Author: William D. DePond, M.D. (see Authors page)

Revised: 2 July 2018, last major update July 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Severe chronic active EBV infection [title]

Related Topics: Epstein Barr virus

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Cite this page: DePond, W. D. Severe chronic active EBV infection. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesebvsevere.html. Accessed December 9th, 2019.
Definition / general
  • Rare, life threatening
  • Criteria: chronic or recurrent infectious mononucleosis-like symptoms lasting more than 6 months and high titers of EBV antibodies
Case reports
Gross images

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Enlarged spleen

Microscopic (histologic) images

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Infiltration of lymphoplasma cells and erythrophagocytic histiocytes

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Intranuclear positive signals

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CD3+ T lymphocytes

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Infiltrated lymphoid cells

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Infiltrated lymphocytes expressing CD8

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