Lymph nodes - not lymphoma
Inflammatory disorders (noninfectious)
Granulomatous inflammation

Author: William D. DePond, M.D. (see Authors page)

Revised: 29 June 2018, last major update June 2006

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Granulomatous inflammation[TI] lymph node

Cite this page: DePond, W.D. Granulomatous inflammation. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesgranulomatous.html. Accessed August 17th, 2018.
Definition / general
  • Due to infection (atypical mycobacteria is common), foreign bodies, secondary response to malignancy
  • Helpful diagnostic features include presence and type of necrosis; presence and type of giant cells; size, shape and distribution of granulomas; other associated changes
  • These lymph nodes should be cultured
Case reports
  • 69 year old woman with granulomatous reaction around cholesterol-like clefts, apparently due to draining fluid from an ovarian mucinous cystadenoma (Arch Pathol Lab Med 1985;109:1124)
Gross images

Images hosted on other servers:

Extensive involvement by granuloma and fibrosis

Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Dr. Mark R. Wick:

Necrotizing granuloma


AFIP images:

Necrotizing granulomatous lymphadenitis



Images hosted on other servers:

Granduloma due to lymphangiogram contrast media in lymph node