Lymph nodes - not lymphoma
Infectious / parasitic disorders
HHV8/KHSV

Author: William D. DePond, M.D. (see Authors page)

Revised: 3 July 2018, last major update July 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: HHV8 [title] lymph nodes

Table of Contents
Definition / general
Cite this page: DePond, W. D. HHV8/KHSV. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodeshhv8.html. Accessed July 21st, 2018.
Definition / general
  • Human herpesvirus 8 / Kaposi sarcoma associated herpesvirus
  • High prevalence in East Africa
  • Associated with Kaposi sarcoma (Mod Pathol 2004;17:456); in endemic regions of Africa, association is independent of HIV status (Hum Pathol 2006;37:23)
  • Also associated with primary effusion lymphoma, plasmablastic lymphoma, some cases of multicentric Castleman disease
  • Note: most lymphomas are HHV8-, even in HHV8+ patients
  • Not associated with Kikuchi disease (Hum Pathol 2003;34:130), despite earlier study to the contrary (Hum Pathol 1998;29:1091)